High Quality Content by WIKIPEDIA articles! Prazitone (AGN-511) is a barbiturate derivative invented in the 1970s. Unlike most barbiturates, it has little or no sedative effects, instead acting as a non-sedating anxiolytic and antidepressant. The dosage range in humans is around 200-600 mg, although higher doses have been used in trials for the treatment of depression associated with Parkinson`s disease.