High Quality Content by WIKIPEDIA articles! The Pre-Pottery Neolithic (PPN, around 8,500-5,500 BCE) represents the early Neolithic in the Levantine and upper Mesopotamian region of the Fertile Crescent. It succeeds the Natufian culture of the Epipaleolithic (Mesolithic) as the domestication of plants and animals was in its beginnings and triggered by the Younger Dryas. The Pre-Pottery Neolithic culture came to an end around the time of the 8.2 kiloyear event, a cool spell lasting several hundred years centred around 6200 BCE.