High Quality Content by WIKIPEDIA articles! Professor James Moriarty is a fictional character and the archenemy of the detective Sherlock Holmes in the fiction of Sir Arthur Conan Doyle. Moriarty is a criminal mastermind, described by Holmes as the "Napoleon of Crime". Doyle lifted the phrase from a real Scotland Yard inspector who was referring to Adam Worth, one of the real life models of Moriarty. The character of Moriarty as Holmes` greatest enemy was introduced primarily as a narrative device to enable Conan Doyle to kill off Sherlock Holmes, and only featured directly in two of the Sherlock Holmes stories. However, in more recent derivative work he is often given a greater prominence and treated as Holmes` primary antagonist.