Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. A protein microarray, sometimes referred to as a protein binding microarray, provides a multiplex approach to identify protein–protein interactions, to identify the substrates of protein kinases, to identify transcription factor protein-activation, or to identify the targets of biologically active small molecules. The array is a piece of glass on which different molecules of protein or specific DNA binding sequences (as capture probes for the proteins) have been affixed at separate locations in an ordered manner thus forming a microscopic array. The most common protein microarray is the antibody microarray, where antibodies are spotted onto the protein chip and are used as capture molecules to detect proteins from cell lysate solutions. Related microarray technologies also include DNA microarrays, cellular microarrays, antibody microarrays, tissue microarrays and chemical compound microarrays.

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