Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Prova is an open source programming language that combines Prolog with Java. Prova is a rule-based scripting system that is used for middleware. The language combines imperative and declarative programming by using a prolog syntax that allows calls to Java functions. In this way a strong Java code base is combined with Prolog features such as backtracking. Prova is derived from Mandarax, a Java-based inference system developed by Jens Dietrich. Prova extends Mandarax by providing a proper language syntax, native syntax integration with Java, agent messaging and reaction rules. The development of this language was supported by the grant provided within the EU projects GeneStream and BioGRID. In the project, the language is used as a rule-based backbone for distributed web applications in biomedical data integration, in particular, the GoPubMed system.

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