Quantitative susceptibility mapping

Quantitative susceptibility mapping

Jesse Russell Ronald Cohn

     

бумажная книга



ISBN: 978-5-5147-4134-2

High Quality Content by WIKIPEDIA articles! Quantitative Susceptibility Mapping (QSM) provides a novelcontrast mechanism in Magnetic Resonance Imaging (MRI) different from traditional Susceptibility Weighted Imaging. The voxel intensity in QSM is linearly proportional to the underlying tissue apparent magnetic susceptibility, which is useful for chemical identification and quantification of specific biomarkers including iron, calcium, gadolinium, and super paramagnetic iron oxide (SPIO) nano-particles. QSM utilizes phase images, solves the magnetic field to susceptibility source inverse problem, and generates a three dimensional susceptibility distribution. Due to its quantitative nature and sensitivity to certain kinds of material, potential QSM applications include standardized quantitative stratification of cerebral microbleeds and neurodegenerative disease, accurate gadolinium quantification in contrast enhanced MRI, and direct monitoring of targeted theranostic drug biodistribution in nanomedicine.