High Quality Content by WIKIPEDIA articles! Radiation Induced Cognitive Decline describes the possible correllation between radiation therapy and mild cognitive impairment. Radiation therapy is used mainly in the treatment of cancer. Radiation therapy can be used to cure care or shrink tumors that are interferring with quality of life. Sometimes radiation therapy is used alone; other times it is used in conjunction with chemotherapy and surgery. For people with brain tumors, radiation can be an effective treatment because chemotherapy is often less effective due to the blood-brain barrier. Unfortunately for some patients, as time passes people who received radiation therapy may begin experiencing deficits in their learning, memory, and spatial information processing abilities. The learning, memory, and spatial information processing abilities are dependent on proper hippocampus functionality. Therefore any hippocampus dysfunction will result in deficits in learning, memory, and spatial information processing ability.