High Quality Content by WIKIPEDIA articles! Rhodanine is an organic compound derived from thiazolidine. Rhodanine can be prepared by the reaction of carbon disulfide, ammonia, and chloroacetic acid. Some derivatives of rhodanine have pharmacological properties, such as epalrestat which is used to treat diabetic neuropathy. Thiazolidines are a class of heterocyclic organic compounds with a 5-membered saturated ring with a thioether group and an amine group in the 1 and 3 positions, respectively. It is a sulfur analogue of oxazolidine. The drug pioglitazone contains a thiazolidine ring. It is a drug usually indicated in cases of type II diabetes for decreasing blood sugar. It also decreases triglycerides and C-reactive protein levels. It lowers blood pressure and increases levels of HDL. Another drug which contains a thiazolidine ring is the antibiotic drug penicillin.

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