High Quality Content by WIKIPEDIA articles! The Roman–Persian Wars were a series of conflicts between states of the Greco-Roman world and two successive Iranic empires: the Parthian and the Sassanid. Contact between the Parthian Empire and the Roman Republic began in 92 BC; wars began under the late Republic, and continued through the Roman and Sassanid empires. They were brought to an end by the Arab Muslim invasions, which struck the Sassanid and Byzantine East Roman empires with shattering effect shortly after the end of the last war between them.