High Quality Content by WIKIPEDIA articles! The scleraxis protein is a member of the basic-helix-loop-helix (bHLH) superfamily of transcription factors. Currently two genes (SCXA and SCXB respectively) have been identified to code for identical scleraxis proteins.It is thought that early scleraxis expressing progenitor cells lead to the eventual formation of tendon tissue and other muscle attachments. Scleraxis is involved in mesoderm formation and is expressed in the syndetomal (embryonic tissues that develop into tendon and blood vessels) compartment of developing somites (primitive segments or compartments of embryos).

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