Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Small nucleolar RNA psi28S-3316 is a member of the H/ACA class of snoRNA. This family is responsible for guiding the modification of uridine 3316 in Drosophila 28S rRNA to pseudouridine. Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs. There are two main classes of snoRNA, the C/D box snoRNAs which are associated with methylation, and the H/ACA box snoRNAs which are associated with pseudouridylation. snoRNAs are commonly referred to as guide RNAs but should not be confused with the guide RNAs that direct RNA editing in trypanosomes.

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