High Quality Content by WIKIPEDIA articles! Sodium-hydrogen antiporter 3 or Sodium-hydrogen exchanger 3 (NHE3) is an isoform of sodium-hydrogen antiporters. It is found in the nephron of the kidney and in the apical membrane of enterocytes of the intestine. It is primarily responsible for maintaining the balance of sodium. The sodium-hydrogen antiporter or sodium-hydrogen exchanger is a protein found in the nephron of the kidney. It is primarily responsible for maintaining the balance of sodium. Nephron is the basic structural and functional unit of the kidney. Its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH.

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