High Quality Content by WIKIPEDIA articles! Southern Illinois University Edwardsville, commonly abbreviated SIUE, is a four-year coed public university in Edwardsville, Illinois about 20 miles (32 km) from St. Louis, Missouri. SIUE was established in 1957 as an extension of Southern Illinois University Carbondale, and is the younger of the two largest institutions of Southern Illinois University. The University offers graduate programs through its Graduate School.