High Quality Content by WIKIPEDIA articles! Spoleto (Latin Spoletium) is an ancient city in the Italian province of Perugia in east central Umbria on a foothill of the Apennines. It is 20 km (12 mi) S. of Trevi, 29 km (18 mi) N. of Terni, 63 km (39 mi) SE of Perugia; 212 km (132 mi) SE of Florence; and 126 km (78 mi) N of Rome.