High Quality Content by WIKIPEDIA articles! The Andy Griffith Show is an American sitcom first televised by CBS between October 3, 1960, and April 1, 1968. Andy Griffith portrays a widowed sheriff in the fictional small community of Mayberry, North Carolina. His life is complicated by an inept but well-meaning deputy, Barney Fife (Don Knotts), a spinster aunt and housekeeper, Aunt Bee (Frances Bavier), and a young son, Opie (Ron Howard, billed as Ronny). Local ne`er-do-wells, bumbling pals, and temperamental girlfriends further complicate his life.