High Quality Content by WIKIPEDIA articles! The Big C is a Showtime original television series created by Darlene Hunt which premiered on August 16, 2010. It drew the largest audience for a Showtime original series premiere in eight years. The second season premiered on June 27, 2011. The third season premiered on April 8, 2012. On July 31, 2012, The Big C was renewed for a fourth and final season, which will begin airing in 2013.