High Quality Content by WIKIPEDIA articles! Transmission electron microscopy DNA sequencing is an emerging third-generation, single-molecule sequencing technology that uses transmission electron microscopy techniques. DNA is visible under the electron microscope; however, it must be labeled with heavy atoms so that the DNA bases can be clearly visualized. In addition, specialized imaging techniques and aberration corrected optics are beneficial for obtaining the resolution required to image the labeled DNA molecule. Transmission electron microscopy DNA sequencing advantageously may provide extremely long read lengths, but it is not yet commercially available.