High Quality Content by WIKIPEDIA articles! The 2012 United States presidential election in South Carolina took place on November 6, 2012 as part of the 2012 General Election in which all 50 states plus The District of Columbia participated. South Carolina voters chose 9 electors to represent them in the Electoral College via a popular vote pitting incumbent Democratic President Barack Obama and his running mate, Vice President Joe Biden, against Republican challenger and former Massachusetts Governor Mitt Romney and his running mate, Congressman Paul Ryan. Romney defeated Obama in the state by 54.56% to 44.09%, a margin of 10.47%.