High Quality Content by WIKIPEDIA articles! U.S. Route 160 is a 1,465 mile (2,358 km) long east–west United States highway in the Midwestern United States. The western terminus of the route is at U.S. Route 89 five miles (8 km) west of Tuba City, Arizona. The eastern terminus is at U.S. Route 67 and Route 158 southwest of Poplar Bluff, Missouri.