High Quality Content by WIKIPEDIA articles! U.S. Route 220 (US 220) is a part in the U.S. Highway System that runs from Rockingham, North Carolina to Waverly, New York. In Maryland, the federal highway runs 27.35 miles (44.02 km) from the West Virginia state line at the Potomac River in McCoole north to the Pennsylvania state line in Dickens. Known as McMullen Highway for much of its length in Maryland, US 220 is the primary north–south route in central Allegany County, connecting Cumberland with its southern suburbs and Keyser, West Virginia to the south and Bedford, Pennsylvania to the north. The federal highway is part of the National Highway System between the West Virginia state line and Maryland Route 53 (MD 53) in Cresaptown and between Interstate 68 (I-68), with which it is concurrent through Cumberland, and the Pennsylvania state line.