High Quality Content by WIKIPEDIA articles! U.S. Route 278 is a parallel route of U.S. Route 78. It currently runs for 1,074 miles (1,728km) from Hilton Head Island, South Carolina to Wickes, Arkansas at U.S. Highway 71/U.S. Highway 59. It might be notable that it is longer than its parent highway, US Hwy-78. US Hwy-278 passes through the states of South Carolina, Georgia, Alabama, Mississippi, and Arkansas. This highway passes through the cities and towns of Augusta, Covington, Atlanta, Powder Springs, Georgia; Hiram, Georgia; Dallas, Georgia; Rockmart, Georgia; Cedartown, Georgia; Gadsden, Cullman, Alabama; Tupelo, Oxford, Greenville, Mississippi; Monticello, and Hope, Arkansas.