High Quality Content by WIKIPEDIA articles! In the U.S. state of California, U.S. Route 395 (US 395) is a 557-mile (896 km) route which traverses from Interstate 15 near the southern city limits of Hesperia, north to the Oregon state line in Modoc County near Goose Lake. The route clips into Nevada, serving the cities Carson City and Reno, before returning to California.