High Quality Content by WIKIPEDIA articles! U.S. Route 466 (US 466) was an east–west United States highway. Though it reached a length of around 500 miles (805 km), the route was co-signed with other US routes for much of its length. When California deleted most of its U.S. Highways in the mid-1960s, including US 466 in 1964, there was no longer a need for the designation.