High Quality Content by WIKIPEDIA articles! U.S. Route 60 is an east–west United States highway, running 2,670 mi (4,300 km) from the Atlantic Ocean on the east coast in Virginia to western Arizona. Despite the final "0" in its number, indicating a transcontinental designation, the 1926 route formerly ended in Springfield, Missouri, at its intersection with the major U.S. Route 66. In fact, Route 66 was almost given the US Route 60 number.